Lilly’s retatrutide trial shows Type 2 diabetes patients lost up to 60 pounds over 80 weeks
Late-stage trial results for Eli Lilly's retatrutide published in The Lancet and NEJM show unprecedented weight loss in Type 2 diabetes and obesity populations, alongside meaningful A1C reductions and potential remission signals. The data strengthen Lilly's GLP-1 franchise narrative ahead of an expected FDA filing and can raise expectations for future market share and pricing power, while highlighting regulatory and competitive risks from unauthorized copycats.
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Eli Lilly’s GLP-1 drug retatrutide posted late-stage results in The Lancet and the New England Journal of Medicine. The data showed people with Type 2 diabetes lost up to 60 pounds (about 23%), while obese patients without diabetes lost up to 70 pounds (about 25%). The trials also found up to 40% of patients reached an A1C below 5.7%, under the threshold used to diagnose diabetes and prediabetes.