Eli Lilly’s GLP-1 drug retatrutide posted late-stage results in The Lancet and the New England Journal of Medicine. The data showed people with Type 2 diabetes lost up to 60 pounds (about 23%), while obese patients without diabetes lost up to 70 pounds (about 25%). The trials also found up to 40% of patients reached an A1C below 5.7%, under the threshold used to diagnose diabetes and prediabetes.

After the United States and Israel went to war with Iran, average U.S. gasoline prices rose from just under $3 a gallon to about $4.50, while diesel jumped from $3.75 to a record $6.52. The surge has reignited inflation pressures and weighed on consumer sentiment. The share of respondents who said Donald Trump helped the economy fell to 26% in September from 35% in March.

Oil prices surged on Monday after Saudi Arabia shut a key pipeline and talks on the future of the Strait of Hormuz were postponed. The U.S. national average price of diesel rose to a record $6.23 per gallon, up 75% so far this year. The national average price of unleaded regular gasoline climbed to $4.31 per gallon, up more than 45% since the Iran war began.

International oil prices pushed through $100, with Brent crude closing up 3.3% at $101.21 a barrel and WTI up 3.2% at $96.05. Both contracts posted their highest closing levels since May 22. Fresh developments in the U.S.-Iran conflict raised concerns about supply risks in global energy markets.

U.S. Treasury Secretary Scott Bessent sought to cool what he called market “fever,” but a Treasury announcement to repurchase $6 billion of 10- to 20-year government bonds instead coincided with a jump in yields. The 10-year yield climbed to 4.85%, its highest since November 2023, while the 20- and 30-year yields rose to 5.3%. Stocks slipped at midday, with the Nasdaq Composite down 0.8% and the S&P 500 off 0.6%. Investors have also been focused on concerns that the Iran conflict and President Donald Trump’s trade policies could lift inflation, as U.S. national debt has surpassed $40 trillion.

Amazon-owned autonomous driving company Zoox has received the first approval from the U.S. National Highway Traffic Safety Administration (NHTSA) to launch paid robotaxi service without a safety driver or a steering wheel. The approval covers up to 2,500 vehicles per year for each of the next two years. Zoox will start in Las Vegas, with expansion to other markets depending on state requirements. The development is seen as a key regulatory breakthrough for Amazon’s push to commercialize autonomous ride-hailing.

China generated 49.7% of its electricity from coal in the six months to June, marking the first time the share has fallen below 50%. Renewable energy rose to 41.2% over the same period, the first time it exceeded 40%. Wind and solar together accounted for 24.6% of total generation, officials said.

The Nasdaq 100 briefly fell into technical correction territory, down more than 10% from its most recent record high, as chip and memory shares sold off. Sandisk, Western Digital, Seagate, Micron and AMD fell around 10%, while Dell Technologies dropped 13% and Intel declined 7%. Samsung Electronics and SK Hynix slid more than 15% and Kioxia sank 18%, pressuring suppliers tied to AI data centers. The declines followed renewed concern over the pace of AI infrastructure spending after Alphabet raised its projected capital expenditures to as much as $205 billion.

Donald Trump bought 327 stocks on April 8, 2025, including $100,001 — $250,000 of Apple shares. On April 9 he unexpectedly announced a pause in the “Liberation Day” tariffs, sparking a sharp market rally: Apple rose more than 15% in its best day since 1998 and the S&P 500 closed up 9.5%, its eighth-best session on record. The trades were disclosed more than 14 months late and did not appear in regular transaction reports. These details are described in Trump’s annual financial disclosure report.