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Eli Lilly sues six firms over alleged black-market sales of retatrutide before approval

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Eli Lilly escalated enforcement by suing six U.S. firms for allegedly selling black-market versions of its unapproved obesity drug retatrutide, reinforcing FDA guidance that such GLP-1 products are illegal to market or compound. The move highlights regulatory and safety scrutiny around the booming weight-loss market, potentially supporting Lilly's IP protection and brand integrity while underscoring ongoing risks from illicit supply chains and platform/payment enablement.
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Eli Lilly has filed six lawsuits against U.S. businesses it alleges illegally sold black-market versions of its experimental obesity drug retatrutide, which remains in Phase 3 trials. The U.S. FDA has said selling retatrutide and other unapproved versions of GLP-1 products to consumers is illegal and cannot lawfully be compounded. Lilly said it has referred more than 200 individuals and entities to regulators and law enforcement, while U.S. Customs and Border Protection intercepted over 690 illicit GLP-1 drug shipments in fiscal year 2025. The company said it is stepping up efforts to curb unauthorized sales through online channels and other outlets.