GLP-1 drugmakers face lawsuits alleging Ozempic and Zepbound caused permanent vision loss
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GLP-1 drugmakers face a growing wave of lawsuits alleging Ozempic/Zepbound caused NAION-related permanent vision loss, while the FDA investigates a possible link. Although evidence is mixed and companies deny causality, litigation and potential label changes increase regulatory and legal overhang for the category. Near-term, this can pressure sentiment and raise risk premia for exposed pharma names amid heightened headline risk.
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Manufacturers of GLP-1 drugs including Ozempic and Zepbound are facing lawsuits from patients who allege the medications caused permanent eye damage. The cases center on nonarteritic anterior ischemic optic neuropathy (NAION), a rare condition that can lead to sudden and often lasting vision loss. Nearly 100 NAION-related lawsuits have been filed in New Jersey since 2025, with another set of cases coming from Philadelphia, according to USA Today. Novo Nordisk has said semaglutide has a well-established safety profile backed by more than 58 million patient-years of postmarketing exposure.
